Hysteria is a meter that Hysterical Dame has that when filled, causes her to flip out uncontrollably. While Hysteria is active, any command given to the character is going to be done to a certain degree of Hysteria. Certain actions can be done to increase the Hysterics, and some may decrease it. This can be very troublesome when dealing with objects that randomly turn into weapons. Nervous Broad has an equivalent meter.
Hysteria can be overcome eventually over time by getting through your hysterics and dealing with it, or perhaps you just need to call a strapping young fella to come help you out. His card might be in your purse.