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Each of the four main characters of Problem Sleuth has a female alter ego. Upon completion of their Quest of Spirit, each protagonist gains a mysterious spiritual link with their counterpart.
Problem Sleuth's alter ego is Hysterical Dame.
Pickle Inspector's alter ego is Nervous Broad.
Mobster Kingpin's alter ego is Madame Murel.
Ace Dick's imagination is too crude to have a female alter ego, so his alter ego is merely Ace Dick in a Wig called L'il Ace Dick.